Our FieldScreen Service Track Record

We have used our New Molecules service on over 80 projects with a 80% success rate.

Confidentiality prevents us from revealing information about the majority of our past projects but some of our customers have given us permission to disclose details in the cases that are shown in the table below:

Client Target Class Outcome Notes
Large Pharma Chemokine receptor Success 3 diverse series progressed
Large Pharma Enzyme Success Comparison with in-house and competitor methods
Biotech GPCR Success 30% hit rate
Large Pharma Protease Fail Looking for less basic mimics of highly basic compounds
Biotech Metalloprotease Fail No novel metal chelators in database
Biotech Kinase Success >25% hit rate, <60 compounds screened
Biotech Ion channel Success 30% hit rate, ~300 compounds screened
Biotech Ion channel Success 10% hit rate
Biotech Unknown Success Good hit rate
James Black Foundation CCK-2 Success 30% hit rate
Biotech GPCR Success >25% hit rate
Biotech Protease Fail Primary amine required for activity
Biotech GPCR Success Undisclosed hit rate
Biotech CNS target Success Undisclosed hit rate
Wellcome Trust and Edinburgh University 11β-HSD-1 Success 10% hit rate, 3 new series found
Biotech Undisclosed Success Undisclosed hit rate